The Abbott TDx evaluated for T-uptake

The Abbott TDx evaluated for T-uptake

The Abbott TDx therapeutic drug-monitoring system is based on fluorescence polarization. Polarization fluoroimmunoassay makes use of competitive binding, measuring the tracer binding directly, without the need for separation procedures. The attraction of non-radioactive polarization fluoroimmunoassay for the determination of T-uptake is that there is no radiation hazard and that the homogeneous...

Premature degradation of Abbott TDx reagents.

Anomalous serum thyroxin measurements with the Abbott TDx procedure.

We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the...

Cyclosporine measurement by fluorescent polarization immunoassay utilizing Abbott TDx instrument.

WE HAVE evaluated the usefulness of a fluorescent polarization immunoassay (FPIA) utilizing the Abbott TD.· technology for the routine measurements of cyclosporine in whole blood or plasma. This procedure was compared with the Sandoz radioimmunoassay. The evaluation was undertaken in an effort to decrease the radioactive hazard, and contain the reagent and supply costs, as well as to reduce the...

Lack of mezlocillin and piperacillin interference in measurement of vancomycin in the Abbott TDx.

and blood in hemodialysis patients.J AppI Physiol 1967;23:100-8. 3. Shanon IL, Feller RP, Suddick RP. Human parotid saliva urea in renal failure and during dialysis. Arch Oral Biol 1977;22:83-6. 4. von Eisenwiener HG. Kinetische Bestimmung des Harnstoffes mit dem LKB-System. J Clin Chem Clin Biochem 1976;14:261-4. 5. Akai T,Naka K, Yoshikawa C, et a!.Salivaurea nitrogen as an index to renal fun...